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The Effects of Coffee and It’s Chlorogenic Acid in Improved Vascular Function for Prevention of Blood Vessels Related Disease Naturally

Chlorogenic acid, a major bioactive compound found in coffee may have a profound effect in stimulated vascular function in moving blood, some studies suggested.

Vascular function is the action of arteries and veins, involving blood circulation in provided nutrients and fluids to the body cells and tissue, through adjusting the blood flow.

Abnormal vascular function found in image of PR interval in electrocardiography may associate to increase risk of cardiovascular diseases(3).

Image result for Effects of Coffee

The normal of PR interval or period measured in milliseconds, is between 120 and 200ms in duration.

However, “PR-interval length, even in the conventionally normal range, is independently associated with endothelial dysfunction and increased arterial stiffness in healthy subjects free of atherosclerotic disease” said, Dr. Chan YH, the lead scientist.

According to medical literature, abnormal vascular function may increase risk of vascular disease, affecting the circulatory system in induction of peripheral artery, carotid artery and venus disease and blood clot.

The causes of abnormal vascular function are unknown. But researchers agreed that hypertension, hypercholesterolemia, smoking, diabetes mellitus, and obesity are risk factors to the onset of abnormal vascular function.

Although, there are numbers of mechanism contributed to risk of abnormal vascular function, aging is also considered as an independent risk factor, which can lead to progressive worsening of vascular function and structure.

Coffee, a popular and social beverage all over the world, particularly in the West, is a drink made from roasted bean from the Coffea plant, native to tropical Africa and Madagascar.

According to the study lead by the University of Reading, chlorogenic acids isolated from coffee roasted bean, acutely improved vascular function, partly due to  mediation of 5-CQA, a member in the group in regulated the normal function of arteries and veins.

Chlorogenic acid (CGA) is the ester of caffeic acid and (−)-quinic acid with function in modulated lignin biosynthesis in binding to cellulose fibers and hardens and strengthened the plant cell walls.

An acute randomized, controlled, cross-over human intervention trials is conducted by researchers at the University of Reading to examine the impact of coffee intake, matched for caffeine but differing in CQA content (89, and 310 mg) on flow-mediated dilatation (FMD) in 15 healthy male subjects, in compared a second intervention trial conducted with 24 healthy male subjects.

Observation of he impacts of pure 5-caffeoylquinic acid (5-CQA), the main CGA in coffee(5-CQA; 450 mg and 900 mg) on FMD, found that
*. Low and high CGA(89 mg and 310 mg CGA) intake, show a significant effect on vascular function 1 hour after injecting coffee.

*. Coffee intake is  closely associated to the paralleled to the appearance of CGA metabolites in regulated the normal function of arteries and veins at 5 hours

*. 5-CQA (450 mg) expressed an improvement by FMD assay after 1 hour of administration.

The information  suggested that coffee has a strong effect in activated vascular function  through expression of CGA and its metabolites in plasma and numbers of other phytochemicals including 3-, 4- and 5-feruloylquinic acid and ferulic-4′-O-sulfate at 1 h and isoferulic-3′-O-glucuronide and ferulic-4′-O-sulfate.

Interestingly, in the further illustration of coffee and its CGA effect on vascular abnormality, researchers at the joint study lead by the Bioactive Substance Research Group, University of Antioquia, Medellín, Colombia, launched an investigation of participant including 38 men and 37 women with a mean ± SD age of 38.5 and body mass index of 24.1 and randomly assigned to 3 groups*  A control group that did not consume coffee or a placebo

*Group consumed 400 mL coffee/d for 8 wk containing a medium (MCCGA; 420 mg) or

*Group consumed 400 mL coffee/d for 8 wk containing a medium high  CGA content,

At the end of the experiment, researchers concluded

*. Coffee consumption over the period indicated and after 1 hours, show a significant presence of caffeic and ferulic acid concentrations in the coffee-drinking groups, with different values in 2 coffee injection group.

*  At the same time, the levels of antioxidant expression increased substantially in 2 coffee intake group, but undetectable in control group or placebo.

* All amount of antioxidants and phytochemicals creased to exist after 8 weeks.

These results indicated the efficacy of  tested acid not only has a strong implication in promoted vascular function in blood circulation but also exerted a similar function of Nonsteroidal Anti-inflammatory Drugs (NSAIDs) in decreased inflammation and prevented blood clots through its antioxidant properties.

The evidences in the study demonstrated a acute effect of coffee in promoting of vascular function in improved nutrients and fluids transportation by arteries and vessels.

Taking together, there is no doubt that coffee consumption have an enormous effect in improved vascular function in reduced risk of vascular diseases and diseases’ complications.

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Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it’s news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada – Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Mediation of coffee-induced improvements in human vascular function by chlorogenic acids and its metabolites: Two randomized, controlled, crossover intervention trials by Mills CE1, Flury A2, Marmet C3, Poquet L3, Rimoldi SF2, Sartori C4, Rexhaj E2, Brenner R2, Allemann Y2, Zimmermann D3, Gibson GR1, Mottram DS1, Oruna-Concha MJ1, Actis-Goretta L3, Spencer JP5.(PubMed)
(2) Coffee Consumption Increases the Antioxidant Capacity of Plasma and Has No Effect on the Lipid Profile or Vascular Function in Healthy Adults in a Randomized Controlled Trial by Agudelo-Ochoa GM1, Pulgarín-Zapata IC2, Velásquez-Rodriguez CM3, Duque-Ramírez M4, Naranjo-Cano M5, Quintero-Ortiz MM5, Lara-Guzmán OJ6, Muñoz-Durango K2.(PubMed)
(3) Abnormal vascular function in PR-interval prolongation by Chan YH1, Siu CW, Yiu KH, Li SW, Lau KK, Lam TH, Lau CP, Tse HF(PubMed)

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Veteran Owned Coffee Company Releases Best Commercial Ever: “I’ve Had People Call My Videos Offensive… Well… F*** You”

blackriflecoffee1

Today’s hypersensitive snowflake world of boycotts and mass protests over seemingly unimportant things has led many a company to remain silent for fear of retribution from the the left.

But one company that’s quite literally sticking to its guns and could not care less about the virtue signaling and faux outrage is veteran owned Black Rifle Coffee.

Without a doubt, the following commercial, featuring owner Evan Hafer will lead to mass triggerings from coast to coast.

Definitely worth watching (** Strong Language **):

Veteran Owned Coffee Company Releases Best Commercial Ever: “I’ve Had People Call My Videos Offensive… Well… F*** You”

And just in case you demand more, here’s a commercial in which they objectify women… err… coffee.

How to make Covfefe: “Tastes Like Freedom!”
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The Best Way to Store Coffee for the Long Haul

A world without coffee is not a world most people would want to live in. It makes sense, then, that figuring out how to properly store your coffee should be high on yourlist for your emergency food

supply.  After all, a steaming hot cup of Joe is a great moral booster while you are sitting out an emergency. Like everything else, a little planning goes a long way; there are a few things to consider when prepping coffee beans for long-term storage.

Storing Pre-roasted Beans

Pre-roasted coffee beans are readily available almost everywhere—from coffee shops to grocery stores to gas stations, and they can easily be purchased online as well. They are more affordable when purchased in bulk and easy to grind for your personal use immediately. Like most foods that you want to store for a long period of time, you need to remove them from their sale packaging and keep your beans in airtight containers away from light, air, and moisture.

It’s important to remember though, that pre-roasted coffee beans immediately begin losing their freshness upon roasting. Even in airtight containers or mylar storage bags (see the proper techniques for food storage here) roasted beans will only last around 6 weeks in storage. If using pre-roasted beans is important to you, you’ll need to replenish/rotate your storage every few weeks. To me this seems like a hassle, because I’d rather have a bulk quantity ready to go for the long haul. The solution is storing green coffee beans and roasting them on your own when you’re ready to use them, but many people shy away from roasting their own beans (though they shouldn’t, as I’ll explain below).

Storing Green Coffee Beans

Purchasing green coffee beans is far cheaper than purchasing roasted coffee beans. To compare, a 25-pound bag goes for around $105 dollars—that’s close to the price of a 12-pound bag of roasted beans! Besides, green coffee beans maintain freshness for several years (you might want to rotate your supply after 2 years just to be on the safe side). But how do you go about roasting your own beans? Do you need a bunch of fancy equipment and a barista’s knowledge of coffee? Not at all–a cheap popcorn popper or a frying pan and you’ll be good to go.

The Popcorn Popper Method

The Frying Pan Method

In a catastrophic situation where electricity is unavailable, all you need to remember are the tenants of the above videos: use a soft, indirect heat, keep the beans moving, and don’t let them roast for too long.

Pamela Bofferding is a native Texan who now lives with her husband and sons in New York City. She enjoys hiking, traveling, and playing with her dogs.

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Coffee Is A Drug, It’s a ‘Good’ One

Could coffee do more than just stimulate alertness and stress out the adrenals? What if there was more going on to this ritualistic beverage consumed by billions around the world than just caffeine addiction? What if it was medicine for both the body and soul? 

That coffee possesses ‘drug-like’ properties, we know quite well. Some of us, in fact, revel in its addictive properties, as it comes with a certain — albeit a tad bit pathological —  industriousness. After all, is there anyone more disciplined/obsessed than a coffee drinker — at least, that is, when it comes to acquiring and drinking coffee? You can set your clocks with exactitude to the performance of their daily coffee-associated machinations, to the point where some coffee makers already have built in clocks, so as not to delay or miss any opportunity for its owner to imbibe.  The type of sober religiosity required to turn drinking a beverage into a ritual is known only by a few Zen tea drinkers and quite possibly billions of habitual coffee drinkers.

It is inhumane, in my opinion, to force people who have a genuine medical need for coffee to wait in line behind people who apparently view it as some kind of recreational activity.” ~ David Barry

Let us also not forget that one of the first documented uses of coffee over 500 years ago was in the Sufi monasteries of Yemen where coffee was known as qahhwat al-bun, or, the ‘wine of the bean,’ the phrase which provided the etymological origin of the word coffee.  Once lauded as a “miracle drug” and used as a sacrament in late-night rituals to invoke the sensation of God within revelers, still today, coffee drinkers are known to cast themselves into bouts of coffee-drinking induced reverie and enthusiasm (literally: en “in”  + theos “god” or “god-filled”) by drinking this strangely intoxicating, and yet somehow still sobering concoction.

It is interesting that even addictions can be viewed as a form of ritual — albeit degenerated ones performed semi- or subconsciously.  But that cup of Joe gets many of us up in the morning to perform our secular duties, which says a lot considering what many of us are forced or coerced to do for a living.

While many attribute coffee’s vice-like hold on their physiology to its caffeine content, there is much more going on than simply a fixation on a ‘stimulant.’ It has been known for over a quarter of a century that coffee contains a compound known as cafestrol with significant opiate-like properties and which is found within both caffeinated and decaffeinated coffee forms. The ‘narcotic’ properties of coffee, therefore, are no doubt due to a complex interplay between a wide range of compounds — not just a stimulant, but an opioid agonist as well.

Coffee is also a ‘brain-booster’ and contains a compound called trigonelline which in vitro research both stimulates the release of dopamine (not unlike cocaine), and stimulates neurite outgrowth, which involves the extension of dendrites and axons in neurons and which may compensate and rescue damaged neuronal networks in the aging brain.

One of history’s greatest nutrition philosophers, Rudolf Hauschka, described coffee’s action on our body-mind as follows:

Coffee makes us more aware of our bodily structure. And since this structure is so wise and logical, our thoughts become logical in their awareness of it. Coffee thus helps thinking to find a firm foundation. The connection between bodily being and thinking, keeps calling itself to our attention. Coffee has the same effect on digestion that thought has on our upper man, i.e., a properly ordered metabolism goes hand in hand with orderly thinking. Both are founded on a properly ordered physical structure.” ~ Rudolf Hauschka, Nutrition: A Holistic Approach

Coffee is also one of the only sources of “bitters” remaining in the sweet-fixated Western diet, which sadly comes with a certificate of guarantee that the bearer will likely develop type 2 diabetes, heart disease or a receive a cancer diagnosis at some point in their life. Could the extreme bitterness of coffee be the reason why it has been repeatedly shown to reduce type 2 diabetes risk, as it is one of the only ways we can balance out the highly inappropriate excesses of carbohydrate in our modern dietary configuration?

We don’t normally think of grains as sweet, but they are on the glycemic index. Puffed rice, for instance, can make the blood sweeter than white sugar which is why carbs are known as “crouching diabetes, hidden sugar.” Coffee contains a wide range of blood-glucose and insulin sensitizing compounds, making it an ideal complement to a carbohydrate-deranged diet.

Coffee also awakens and stimulates the Qi, as it is known in the Chinese medical tradition. This was recently discussed in an article entitled “Similarity between the effects of coffee and qi stimulating events“. While raising Qi through exercise and energy work is the ideal situation, coffee provides a short-cut which is the modus operandi in the modern world: instant gratification in exchange for (energy) indebtedness.

When used responsibly,* however, coffee may be a great boon to health. There are in fact over 80 health conditions which may respond favorably to its use, or whose risk will be reduced through its consumption, as documented on our coffee research database node. Just make sure its organic and prepared with clean, toxicant-free water. Learn more about coffee’s potential health benefits by clicking the image below:

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