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The Effects of Coffee and It’s Chlorogenic Acid in Improved Vascular Function for Prevention of Blood Vessels Related Disease Naturally

Chlorogenic acid, a major bioactive compound found in coffee may have a profound effect in stimulated vascular function in moving blood, some studies suggested.

Vascular function is the action of arteries and veins, involving blood circulation in provided nutrients and fluids to the body cells and tissue, through adjusting the blood flow.

Abnormal vascular function found in image of PR interval in electrocardiography may associate to increase risk of cardiovascular diseases(3).

Image result for Effects of Coffee

The normal of PR interval or period measured in milliseconds, is between 120 and 200ms in duration.

However, “PR-interval length, even in the conventionally normal range, is independently associated with endothelial dysfunction and increased arterial stiffness in healthy subjects free of atherosclerotic disease” said, Dr. Chan YH, the lead scientist.

According to medical literature, abnormal vascular function may increase risk of vascular disease, affecting the circulatory system in induction of peripheral artery, carotid artery and venus disease and blood clot.

The causes of abnormal vascular function are unknown. But researchers agreed that hypertension, hypercholesterolemia, smoking, diabetes mellitus, and obesity are risk factors to the onset of abnormal vascular function.

Although, there are numbers of mechanism contributed to risk of abnormal vascular function, aging is also considered as an independent risk factor, which can lead to progressive worsening of vascular function and structure.

Coffee, a popular and social beverage all over the world, particularly in the West, is a drink made from roasted bean from the Coffea plant, native to tropical Africa and Madagascar.

According to the study lead by the University of Reading, chlorogenic acids isolated from coffee roasted bean, acutely improved vascular function, partly due to  mediation of 5-CQA, a member in the group in regulated the normal function of arteries and veins.

Chlorogenic acid (CGA) is the ester of caffeic acid and (−)-quinic acid with function in modulated lignin biosynthesis in binding to cellulose fibers and hardens and strengthened the plant cell walls.

An acute randomized, controlled, cross-over human intervention trials is conducted by researchers at the University of Reading to examine the impact of coffee intake, matched for caffeine but differing in CQA content (89, and 310 mg) on flow-mediated dilatation (FMD) in 15 healthy male subjects, in compared a second intervention trial conducted with 24 healthy male subjects.

Observation of he impacts of pure 5-caffeoylquinic acid (5-CQA), the main CGA in coffee(5-CQA; 450 mg and 900 mg) on FMD, found that
*. Low and high CGA(89 mg and 310 mg CGA) intake, show a significant effect on vascular function 1 hour after injecting coffee.

*. Coffee intake is  closely associated to the paralleled to the appearance of CGA metabolites in regulated the normal function of arteries and veins at 5 hours

*. 5-CQA (450 mg) expressed an improvement by FMD assay after 1 hour of administration.

The information  suggested that coffee has a strong effect in activated vascular function  through expression of CGA and its metabolites in plasma and numbers of other phytochemicals including 3-, 4- and 5-feruloylquinic acid and ferulic-4′-O-sulfate at 1 h and isoferulic-3′-O-glucuronide and ferulic-4′-O-sulfate.

Interestingly, in the further illustration of coffee and its CGA effect on vascular abnormality, researchers at the joint study lead by the Bioactive Substance Research Group, University of Antioquia, Medellín, Colombia, launched an investigation of participant including 38 men and 37 women with a mean ± SD age of 38.5 and body mass index of 24.1 and randomly assigned to 3 groups*  A control group that did not consume coffee or a placebo

*Group consumed 400 mL coffee/d for 8 wk containing a medium (MCCGA; 420 mg) or

*Group consumed 400 mL coffee/d for 8 wk containing a medium high  CGA content,

At the end of the experiment, researchers concluded

*. Coffee consumption over the period indicated and after 1 hours, show a significant presence of caffeic and ferulic acid concentrations in the coffee-drinking groups, with different values in 2 coffee injection group.

*  At the same time, the levels of antioxidant expression increased substantially in 2 coffee intake group, but undetectable in control group or placebo.

* All amount of antioxidants and phytochemicals creased to exist after 8 weeks.

These results indicated the efficacy of  tested acid not only has a strong implication in promoted vascular function in blood circulation but also exerted a similar function of Nonsteroidal Anti-inflammatory Drugs (NSAIDs) in decreased inflammation and prevented blood clots through its antioxidant properties.

The evidences in the study demonstrated a acute effect of coffee in promoting of vascular function in improved nutrients and fluids transportation by arteries and vessels.

Taking together, there is no doubt that coffee consumption have an enormous effect in improved vascular function in reduced risk of vascular diseases and diseases’ complications.

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Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it’s news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada – Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

(1) Mediation of coffee-induced improvements in human vascular function by chlorogenic acids and its metabolites: Two randomized, controlled, crossover intervention trials by Mills CE1, Flury A2, Marmet C3, Poquet L3, Rimoldi SF2, Sartori C4, Rexhaj E2, Brenner R2, Allemann Y2, Zimmermann D3, Gibson GR1, Mottram DS1, Oruna-Concha MJ1, Actis-Goretta L3, Spencer JP5.(PubMed)
(2) Coffee Consumption Increases the Antioxidant Capacity of Plasma and Has No Effect on the Lipid Profile or Vascular Function in Healthy Adults in a Randomized Controlled Trial by Agudelo-Ochoa GM1, Pulgarín-Zapata IC2, Velásquez-Rodriguez CM3, Duque-Ramírez M4, Naranjo-Cano M5, Quintero-Ortiz MM5, Lara-Guzmán OJ6, Muñoz-Durango K2.(PubMed)
(3) Abnormal vascular function in PR-interval prolongation by Chan YH1, Siu CW, Yiu KH, Li SW, Lau KK, Lam TH, Lau CP, Tse HF(PubMed)

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How to Protect Your Heart Against Onset of Cardiovascular Disease (CVD), Revealed by National Institutes of Health Studies

Carrots’ carotenoids may have a profound and positive effect in protection of your heart against development of cardiovascular disease, some scientists suggested.

The differentiation of studies were carried out by some respectable institutes, including the Università di Napoli and published on online medical data.Image result for cardiovascular disease

Carotenoids used by the plant to absorb light energy in photosynthesis, are class of mainly yellow, orange, or red fat-soluble pigments, including α-carotene, β-carotene, lutein, zeaxanthin.and lycopene,


In plants, carotenoids play an important role in protected chlorophyll from sunlight in induction of oxidation to cause photo damage.


Researcher at the Tufts University suggested that in human, dietary carotenoids may provide health benefits in decreasing risk of diseases, particularly certain cancers and eye disease.


Cardiovascular disease is a medical condition characterized by heart attack, chest pain (angina) or stroke cause by narrowed or blocked blood vessels.

Most common symptoms included chest pain, chest tightness, chest pressure and chest discomfort (angina), shortness of breath. sweating, irregular heartbeat


If you experience some the above symptoms, please see your doctor right the way.


A rest electrocardiogram (ECG or EKG) can often detect heart disease, heart attack, an enlarged heart, or abnormal heart rhythms that may induce heart failure.


Rocket, UCSF – Virtual Labs, Stanford University in the evaluation CARDIOVASCULAR COMPLICATIONS suggested,  “Cardiovascular disease (CVD) is the leading cause of death among people with diabetes mellitus” and “Compared to people without diabetes, those with diabetes have a higher prevalence of CVD and are more likely to have myocardial infarctions or silent myocardial ischemia”.


However, diabetic patients who actively manage their risk factors may avoid or delay the development of heart and blood vessel disease.


Carrot, a root vegetable with orange color is a sub spices of Daucus carota, belongings to the family Apiaceae, native to Asian and Europe.

1. Carbohydrates
2. Sugars
3. Fibre
4. Fat
5. Protein
6. Vitamin A
7. Thiamine (VittaminB1)
8. Riboflavin (Vittamin B2)
9. Niacin (Vittamin B3)
10. Vitamin B6
11. Folate (Vittamin B9)
12. Vitamin C
13. Vitamin K
14. Calcium
15. Iron
16. Magnesium
17. Molybdenum
18. Phosphorus
19. Potassium
20. Sodium

In the study to evaluate the effect of many natural substances, including carotenoids in protection against cardiovascular disease through influence of endothelial functions, smooth muscle cell proliferation, thrombosis and plaque rupture, researchers at the Seconda Università di Napoli lauched an study to know more of the injection of the pigment in inhibition of ROS which were found over expression in patients with CVD.


ROS, the reactive oxygen species produced through many aspects and have a strong implications in all organs and tissues in the body daily.


Dr. Giugliano D, said, “A sufficient supply with antioxidants from diet might help prevent or delay the occurrence of pathological changes associated with oxidative stress” and ” When diet fails to meet the antioxidant requirement, dietary supplements might be indicated”.


Injection of antioxidants from various sources together with the antioxidants produced by the body tissues play an important role to keep free radicals in check.

In other words, maintaining the healthy ratio of free radicals and antioxidants in the body is considered as a good way to prevent he occurrence of pathological changes and reduce risk of Cardiovascular Disease (CVD).

The best antioxidant frequnetly mentioned by the studies were vitamin E, vitamin C, carotenoids, coenzyme Q10, flavonoids and the amino acid L-arginine.


Oxidative stress was found to induce intracellular Ca2+-overload, one of the critical impact in the genesis of myocyte dysfunction.


Increased expression of free radicals was also found to injure and damage the cardiac myocytes.


Further analysis of the bioactive lycopene, one of the major component of carotenoids, researchers at the Catholic University School of Medicine, conducted a study by comparison to the Northern European or other Western countries, the Mediterranean area in rates of mortality from cardiovascular diseases.


Lycopene, a member of natural carotenoids found in tomato and carrot, is an essential component of the Mediterranean diet.


The study included the identification and differentiation of numbers of study which were satisfied the guidelines and criteria to maintain the integration of the investigations.


According to the selected studies, researchers found that most reports show a strong support of the role of lycopene in the prevention of CVD epidemiologically in a dose-response manner.


However, Dr. Mordente A, the lead author said, ” A less clear and more complex picture emerges from the interventional trials, where several works have reported conflicting results”.


Truly, lycopene reduced risk in prevention of CVD was attributed to its function as an antioxidant scavenger, hypolipaemic agent, inhibitor of pro-inflammatory and pro-thrombotic factors, which have been contributed to attenuated onset of the diseases.


Moreover, in the review of medical literature published between 2000 and 2011 in analysis of the properties of the carotenoid lycopene in chemical and biological systems in preventing cardiovascular diseases (CVD), researchers at the joint study lead by the J Friedrich Schiller University showed that
* Epidemiological studies strongly supported the role of lycopene protective effects against the progression of CVD.

* Lycopene inhibited over expression of low density lipoproteins (LDL) which  is a fundamental mechanism in the initiation of atherosclerosis.

* Lycopene improves blood flow and reduces inflammatory responses.


Dr. Müller L, the lead author after taking into account of other co and confounders said, “Tissue culture experiments and animal studies support potential cardioprotective effects for lycopene and other carotenoids in the blood” and “Most studies showed beneficial effects of lycopeneto individuals who are antioxidant-deficient like elderly patients, or humans exposed to higher levels of oxidative stress like smokers, diabetics, hemodialysis patients and acute myocardial infarction patients”.


The information findings suggested that carrot and its bioactive phytochemical carotenoids (lycopene) may have a strong implication in prevent onset of cardiovascular disease, through its antioxidant activity in inhibition of several major risk factors, including levels of low blood cholesterol, Ca2+-overload.

Natural Medicine for Fatty Liver And Obesity Reversal – The Revolutionary Findings To Achieve Optimal Health And Loose Weight

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it’s news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada – Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

(1) Dietary antioxidants for cardiovascular prevention by Giugliano D1(PubMed)
(2) Lycopene and cardiovascular diseases: an update by Mordente A1, Guantario B, Meucci E, Silvestrini A, Lombardi E, Martorana GE, Giardina B, Böhm V(PubMed)
(3) Lycopene and Its Antioxidant Role in the Prevention of Cardiovascular Diseases-A Critical Review by Müller L1, Caris-Veyrat C2,3, Lowe G4, Böhm V(PubMed)
(4) CARDIOVASCULAR COMPLICATIONS(Rocket, UCSF – Virtual Labs, Stanford University)
(5) The role of carotenoids in human health by Johnson EJ(PubMed)

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Studies Confirm (Yet Again) Link between Mercury and Autism

Studies Confirm (Yet Again) Link between Mercury and Autism

Two of the most widespread forms of mercury exposure comes from the organic compounds methylmercury (found in fish) and ethylmercury, which makes up 50% of the vaccine preservative thimerosal. The Agency for Toxic Substances and Disease Registry (ATSDR) affirms that young children and fetuses are particularly sensitive to harmful mercury-related effects such as “brain damage, mental retardation, incoordination, blindness, seizures and inability to speak.” This calls into question public health authorities’ aggressive peddling of annual flu shots—many of which contain thimerosal. The influenza vaccine guidelines target all children who are at least six months of age, with two closely spaced doses recommended for very young children in their “first season of vaccination.” They also target pregnant women and women who “might” be pregnant.

Organic mercury can cross the blood-brain barrier, and numerous studies have fingered it as a major offender in increasing the risk of neurodevelopmental disorders such as autism spectrum disorder (ASD), tic disorders, delayed language and attention-deficit/hyperactivity disorder (ADHD). Shamefully, the Centers for Disease Control and Prevention (CDC) refuses to admit that mercury is an ASD risk factor. Instead, it has been left up to other researchers to continue to focus attention on the compelling relationship between mercury and ASD.

Taking stock across studies

Two 2017 studies perform a valuable service by systematically reviewing the totality of published mercury-ASD evidence that has accumulated over the past dozen or so years, in particular. The two studies both come out of Iran, and both employ a technique called meta-analysis, which is a quantitative systematic review. Meta-analytic studies seek to take a step back and draw rigorous conclusions about comparable studies as a group. A key benefit of this approach is that it can consolidate “a large, and often complex, sometimes apparently conflicting, body of literature.”

The meta-analysis approach is a very appropriate tool for taking stock of published studies that compare mercury levels in ASD individuals and healthy controls without ASD. The first meta-analysis (published in the Journal of Trace Elements in Medicine and Biology by Tina Jafari and other researchers at Iran’s Shahrekord University of Medical Sciences) focuses exclusively on mercury. The second study (published in Progress in Neuropsychopharmacology and Biological Psychiatry by Amene Saghazadeh and Nima Rezaei at the Tehran University of Medical Sciences) examines mercury along with other heavy metals such as lead. Both research teams used state-of-the-art statistical techniques to produce unbiased results.

Both studies found significantly higher concentrations of mercury in the red blood cells of ASD patients versus healthy controls, and the first meta-analysis found significantly higher levels in the whole blood of ASD patients.

The two meta-analyses examined mercury levels for each type of specimen or tissue. Both studies found significantly higher concentrations of mercury in the red blood cells of ASD patients versus healthy controls, and the first meta-analysis found significantly higher levels in the whole blood of ASD patients. (The second study also found higher levels of lead in both the red blood cells and blood of individuals with ASD, which is suggestive of possible combined or synergistic effects.)

There were no significant differences in urinary mercury levels in ASD and healthy individuals, but there were interesting findings for mercury levels in hair. In study #1, mercury concentrations were significantly lower in ASD patients compared with healthy subjects—but when the investigators analyzed their results by continent, this result holds only for America but not for Asia, Africa or Europe. Similarly, study #2’s comparison of developed and developing countries found that mercury levels were significantly lower in the hair of ASD patients in developed but not developing countries—and the preponderance of developed-country studies came from the U.S.

Study #1 also affirmed significantly higher mercury levels in ASD brain tissue. However, the number of brain studies identified for the meta-analysis was very small and also somewhat unclear. The authors report pooling the results of three studies, but their reference list and table include just two studies published by Harvard researchers in 2008 and 2014, respectively. (World Mercury Project has asked the authors to clarify this discrepancy.) The 2008 study found a 68.2% increase in cerebellar mercury in autistic brain tissue (from 3.2 to 80.7 pmol g-1) compared with brain tissue of controls (from 0.9 to 35 pmol g-1), but the increase was not statistically significant. On the other hand, there was a statistically significant elevation in a key marker of oxidative stress in the ASD group that was significantly and positively correlated with elevated mercury. The 2014 study detected no difference in mercury levels but again noted elevated oxidative stress in the ASD group.

Interpreting the findings

Researchers note that a properly conducted systematic review or meta-analysis “allows the reader to take into account a whole range of relevant findings from research on a particular topic” and “establish whether the scientific findings are consistent and generalizable across populations [and] settings…and whether findings vary significantly by particular subgroups.” In addition, “mathematically combining data from a series of well-conducted primary studies may provide a more precise estimate of the underlying ‘true effect’ than any individual study.”

In this instance, the two Iranian teams used a variety of techniques to mitigate the potential weaknesses of meta-analyses. These included using multiple databases, search terms and search strategies to identify relevant studies; following established guidelines to assess the quality of each study; investigating sources of and (where appropriate) adjusting for heterogeneity; analyzing subgroup differences (i.e., the distinction between developed and developing countries); and screening for publication bias. The substantial overlap in the individual studies included in each meta-analysis and the comparability of the two teams’ findings offer a further degree of confidence in the results.

To explain the seemingly counterintuitive finding that hair mercury concentrations are lower (rather than higher) in ASD patients versus healthy individuals, Jafari et al. point to the evidence that those with ASD have impaired detoxification pathways and mechanisms. As a result, ASD individuals retain mercury inside the cells rather than being able to effectively excrete it through the hair, stool or urine. The Iranian authors do not delve into the question of why ASD patients in developed (primarily U.S.) versus developing countries are less likely to excrete mercury and more likely to retain a heavy body burden. However, one conspicuous factor that differentiates the U.S. from other developed countries (as well as the rest of the world) may help explain this result: the U.S. promotes a far more burdensome vaccine schedule, laden with heavy metals such as thimerosal and aluminum, and annually insists that moms accept thimerosal-containing flu vaccines for themselves and their young children.

Moreover, some common flu vaccines contain the emulsifier polysorbate 80, which disrupts the blood-brain barrier and helps create an extremely effective delivery system for escorting neurotoxic ethylmercury and other heavy metals straight to the brain.

Research by Burbacher and colleagues compared blood and brain mercury levels in monkeys exposed to methylmercury and ethylmercury. That work showed that ethylmercury, in particular, goes to the brain, gets metabolized into even more toxic inorganic mercury and remains in the brain for years. Moreover, some common flu vaccines contain the emulsifier polysorbate 80, which disrupts the blood-brain barrier and helps create an extremely effective delivery system for escorting neurotoxic ethylmercury and other heavy metals straight to the brain.

Unfortunately, the majority of published studies only measure total mercury, and very few have examined brain tissue. This makes it challenging to zero in on the specific effects and mechanisms associated with exposure to ethylmercury. Given young children’s widespread exposure to ethylmercury in vaccines, there is no excuse for failing to address this research gap—and even less excuse for failing to remove thimerosal from all vaccines.

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Nearly all medical studies are “totally bogus,” warns science writer who echoes the Health Ranger’s criticism of sloppy science

Image: Nearly all medical studies are “totally bogus,” warns science writer who echoes the Health Ranger’s criticism of sloppy science

For many years, Mike Adams, known to millions as the Health Ranger and the founder of Natural News, has been blowing the whistle concerning the loss of scientific integrity and the destruction of the fundamental principles that undergird scientific research, all in the name of the almighty dollar. He has exposed the lies and corporate fraud behind GMO foods, the death culture propelling the war on carbon and the government corruption that props up pharmaceutical firms who kill millions with chemotherapy, toxic vaccines and dangerous medications. Adams and his team have valiantly sought the truth, regardless of trolls, paid critics and Google’s thought police. And thankfully, he’s not alone.

Richard Harris, an award-winning journalist who has reported on and “traveled to all seven continents” as the science correspondent for National Public Radio (NPR), echoes the Health Ranger’s sentiments in his new book entitled “Rigor Mortis: How Sloppy Science Creates Worthless Cures, Crushes Hope, and Waste Billions.” The level of scientific failure Harris speaks about, which was reported by the New York Post, “costs taxpayers excesses of $28 billion a year.” The science writer turned industry critic says wasted dollars, time and the abject failure of non-reproducible studies means that the data and results from any scientific peer-reviewed paper should be taken “with a grain of salt.”

For scientific research to be considered legitimate, other scientists must be able to replicate the results. But that only happens in about half of researched case studies. Even more troubling, up to two-thirds of what is considered “cutting-edge reports, including the discovery of new genes linked to obesity or mental illness are later disconfirmed.” That’s a fancy word for being exposed as a blatant lie. Here’s one example. Thousands of studies were published in prestigious scientific journals which concentrated on melanoma cells and their relationship to breast cancer. Later, it was discovered that the melanoma cells utilized in all those studies were the wrong cells. Harris lamented, “It’s impossible to know how much this sloppy use of the wrong cells has set back research into breast cancer.”

There are many reasons why modern science is in panic mode and the historically rigorous scientific method has been all but eradicated. Harris believes that all scientists carry an “unconscious bias.” They just can’t see outside their own theses. The brutal competition for funding dollars is another huge issue. Government funding has dropped from 33 percent to 17 percent over the past thirty years. Post-doctoral employment is dwindling, giving “a greater incentive to publish splashy counterintuitive studies,” which are often just plain wrong.

The pressure for funding also pushes scientific groups to publish papers that may state a particular hypothesis, even if facts scream otherwise. A prime example of this is the fact that the CDC still proclaims mercury in vaccines is safe, despite evidence to the contrary. All of the Monsanto studies that claim GMOs are perfectly safe are another. The current system also rewards people who are first to postulate a new area of study, even if that research doesn’t stand the test of time.

Stanford professor of medicine John Ioannidis has written about the problems of reproducing scientific results. He’s discovered “tens of thousands of papers” linking certain genes to diseases like depression or obesity and out of all those published scientific papers, only 1.2 percent “had truly positive results.” The professor has also discovered research that has been cited thousands of times, but turns out to be absolutely false. Professor Ioannidis spoke in Chicago in 2016. His speech was titled, “Evidence based medicine has been hijacked.”

Yes, it has. And it’s up to us to demand that science and truth are reunited.

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SCIENCE SHOCK: Almost all medical studies are “bogus” … reproducibility approaches ZERO

Image: SCIENCE SHOCK: Almost all medical studies are “bogus” … reproducibility approaches ZERO

(Natural News) If you’ve ever wanted to read large collections of fake news, look no further than medical science journals such as The Lancet or the British Medical Journal. Almost everything they publish is “bogus,” explains science writer Richard Harris, who writes for NPR, and the result is billions of dollars in fraud, waste and unnecessary expenditures on Big Pharma drugs that simple don’t work.

His new book is called Rigor Mortis: How Sloppy Science Creates Worthless Cures, Crushes Hope, and Wastes Billions, and it reveals the truth about science fraud that I’ve been documenting for years on Natural News and Scientific.news. What truth is that? Most “science” studies don’t hold up under scrutiny, and most of them can’t be reproduced when someone else attempts to perform the same experiment.

The entire apparatus of Big Pharma and FDA approved drugs, in other words, is largely fraudulent. Most drugs simply don’t work on most people, which is exactly why people who take lots of prescription medications almost always see a decline in their health (they get sicker, not healthier).

The bogus nature of bad science is present across every realm of science, by the way: Pharmaceuticals, climate change, psychology, physics, chemistry and more. Climate change is probably the worst of all these, where scientists decide in advance what outcomes they want to see, then work diligently to shape the computer modeling or data sets to achieve the outcome they want. In fact, the entire industry of “climate change science” is rooted in total junk science fraud, buoyed by fabricated science and aggressive demands of social conformity (plus coordinated attempts to smear and discredit any scientists who don’t kowtow to the science totalitarians).

What’s especially notable in all this is that medical science studies are almost always given instant credibility of “real news” even when they are demonstrably fake. Thus, Google’s war on “fake news” will censor information that questions the legitimacy of the faked science studies because Google automatically assumes all medical journals are 100% real and correct at all times. The far more accurate answer is that they are probably only accurate about 1% of the time, which means they’re 99% fake news that Google scores as 100% real. (See more news about Google’s disinformation schemes at Disinfo.news.)

The New York Post has published an outstanding article summarizing the sad state of science today. Read the original article at the New York Post website:

Medical studies are almost always bogus

By Susannah Cahalan

How many times have you encountered a study — on, say, weight loss — that trumpeted one fad, only to see another study discrediting it a week later?

That’s because many medical studies are junk. It’s an open secret in the research community, and it even has a name: “the reproducibility crisis.”

For any study to have legitimacy, it must be replicated, yet only half of medical studies celebrated in newspapers hold water under serious follow-up scrutiny — and about two-thirds of the “sexiest” cutting-edge reports, including the discovery of new genes linked to obesity or mental illness, are later “disconfirmed.”

Though erring is a key part of the scientific process, this level of failure slows scientific progress, wastes time and resources and costs taxpayers excesses of $28 billion a year, writes NPR science correspondent Richard Harris in his book “Rigor Mortis: How Sloppy Science Creates Worthless Cures, Crushes Hope, and Wastes Billions” (Basic Books).

“When you read something, take it with a grain of salt,” Harris tells The Post. “Even the best science can be misleading, and often what you’re reading is not the best science.”

Take one particularly enraging example: For many years research on breast cancer was conducted on misidentified melanoma cells, which means that thousands of papers published in credible scientific journals were actually studying the wrong cancer. “It’s impossible to know how much this sloppy use of the wrong cells has set back research into breast cancer,” writes Harris.

Another study claimed to have invented a blood test that could detect ovarian cancer — which would mean much earlier diagnosis. The research was hailed as a major breakthrough on morning shows and in newspapers. Further scrutiny, though, revealed the only reason the blood test “worked” was because the researchers tested the two batches on two separate days — all the women with ovarian cancer on one day, and without the disease the next. Instead of measuring the differences in the cancer, the blood test had, in fact, measured the day-to-day differences in the machine.

So why are so many tests bogus? Harris has some thoughts.

For one, science is hard. Everything from unconscious bias — the way researchers see their data through the rosy lens of their own theses — to the types of beaker they use or the bedding that they keep mice in can cloud results and derail reproducibility.

Then there is the funding issue. During the heyday of the late ’90s and early aughts, research funding increased until Congress decided to hold funding flat for the next decade, creating an atmosphere of intense, some would say unhealthy, competition among research scientists. Now only 17 percent of grants get funded (compared to a third three decades ago). Add this to the truly terrible job market for post-docs — only 21 percent land tenure track jobs — and there is a greater incentive to publish splashy counterintuitive studies, which have a higher likelihood of being wrong, writes Harris.

One effect of this “pressure to publish” situation is intentional data manipulation, where scientists cherry-pick the information that supports a hypothesis while ignoring the data that doesn’t — an all too common problem in academic research, writes Harris.

“There’s a constant scramble for research dollars. Promotions and tenure depend on making splashy discoveries. There are big rewards for being first, even if the work ultimately fails the test of time,” writes Harris.

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The findings of two new studies add to the growing body of evidence that links soda to serious health problems.

Excess sugar – especially the fructose in sugary drinks – might damage your brain, the new research suggests.

If you think drinking diet soda puts you in the clear, think again: One of the studies found that people who drank diet soda daily were almost three times as likely to develop stroke and dementia when compared to those who did not.

The first study, published in Alzheimer’s & Dementia on March 5, 2017, found that higher consumption of sugary beverages was associated with markers for pre-clinical Alzheimer’s disease.

Researchers looked at 4,000 people who consumed more than two sugary drinks a day of any type – soda, fruit juice, and other soft drinks – or more than three per week of soda alone. Among that “high intake” group, they found multiple signs of accelerated brain aging, including smaller overall brain volume, poorer episodic memory, and a shrunken hippocampus, all risk factors for early-stage Alzheimer’s disease. They also found that higher intake of diet soda – at least one per day – was associated with smaller brain volume.

This study’s results align with earlier research done with smaller samples, including one with 737 middle-aged participants in the Boston Puerto Rican Health Study, which found that higher sugar intake was cross-sectionally associated with Alzheimer’s-like behavioral patterns, reports Bloomberg.

The second study, published in the journal Stroke on April 20, 2017, found “…higher recent and higher cumulative intake of artificially sweetened soft drinks were associated with an increased risk of ischemic stroke, all-cause dementia, and Alzheimer’s disease dementia.” This was after researchers adjusted for age, sex, education (for analysis of dementia), caloric intake, diet quality, physical activity, and smoking. That study concluded “artificially sweetened soft drink consumption was associated with a higher risk of stroke and dementia.”

After measuring volunteers’ beverage intake at three points over seven years, the researchers monitored the volunteers for 10 years, looking for evidence of stroke in 2,888 people over age 45, and dementia in 1,484 participants over age 60. Surprisingly, they found no correlation between sugary beverage intake and stroke or dementia. However, they DID find that people who drank at least one diet soda per day were almost three times as likely to develop stroke and dementia.

Both studies were conducted by researchers at the Boston University School of Medicine. Lead researcher Matthew Pase, a fellow in the MED neurology department and an investigator at the FHS who is corresponding author on both papers, explained that excess sugar has long been associated with cardiovascular and metabolic diseases like obesity, heart disease, and type 2 diabetes, but little is known about its long-term effects on the human brain.

Pase said he chose to study sugary drinks as a way of examining overall sugar consumption.

“It’s difficult to measure overall sugar intake in the diet,” he says, “so we used sugary beverages as a proxy.”

“It was somewhat surprising that diet soda consumption led to these outcomes,” says Pase, noting that while prior studies have linked diet soda intake to stroke risk, the link with dementia was not previously known.

The studies did not differentiate between types of artificial sweeteners, and did not account for other possible sources of artificial sweeteners. Pase says that scientists have proposed various hypotheses about how artificial sweeteners may damage health, from altering gut bacteria to interfering with the brain’s perception of “sweet,” but “we need more work to figure out the underlying mechanisms.”

While the findings of these studies are important, correlation does not necessarily mean causation. The authors of the studies acknowledge that their conclusions do not prove cause and effect, and that more research is needed.

In an accompanying editorial in Stroke, Ralph Sacco, MD, of the University of Miami Miller School of Medicine wrote that Pase’s work

“…encourages further discussion and more research into this question, for even small causal effects would have tremendous effects on public health due to the popularity of both ASB and SSB consumption. The current body of literature is inconclusive about the causal nature of the associations between ASB consumption and risk of stroke, dementia, diabetes mellitus, and the metabolic syndrome. The growing number of epidemiological studies showing strong associations between frequent consumption of ASBs and vascular outcomes, however, suggests that it may not be reasonable to substitute or promote ASBs as healthier alternatives to SSBs. Both sugar-sweetened and artificially sweetened soft drinks may be hard on the brain.”

Sudha Seshadri, a professor of neurology at Boston University School of Medicine (MED) and a faculty member at BU’s Alzheimer’s Disease Center, who is senior author on both papers, said of the research:

“These studies are not the be-all and end-all, but it’s strong data and a very strong suggestion. It looks like there is not very much of an upside to having sugary drinks, and substituting the sugar with artificial sweeteners doesn’t seem to help.”

“Maybe good old-fashioned water is something we need to get used to,” she adds.

If you want to reduce or eliminate your consumption of soda or other sugary or diet drinks, here are some tricks to help you kick the habit.

  • Reduce your intake slowly: Replace one soda per day with water for a week or so. Then try replacing two sodas with two glasses of water, and so on, until you have entirely cut soda (or whatever your regular sugary or diet drink is) out entirely.
  • Track your consumption: Each time you consume soda or a sugary drink, write it down.
  • Keep alternatives on hand: Always have water with you, everywhere you go. If you must add flavor to your water to make it more appealing, try mixing in a splash of juice, or toss in some cucumber slices or berries.
  • Sip on unsweetened tea: Make hot or iced flavored teas – tea companies offer flavors ranging from fruity to chocolatey to spicy.
  • Replace your soda habit: Are there particular times of day when you crave a sugary beverage? When the urge hits, get up and do something to distract yourself. Take a walk, call a friend, fold socks, draw, juggle…do something that keeps you busy.
  • Fake it ’til you make it: Don’t label yourself as a “soda addict” and don’t tell yourself you “can’t” have soft drinks ever again, for the rest of your life. Thinking in extremes and imposing strict rules on yourself only makes things harder and can lead to obsessive thoughts and behaviors…and ultimately, self-sabotage.

Source – The Daily Sheeple

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34 Scientific Studies Showing Adverse Health Effects From Wi-Fi

Here is an excellent collection of scientific papers finding adverse biological effects or damage to health from Wi-Fi signals, Wi-Fi-enabled devices or Wi-Fi frequencies (2.4 or 5 GHz), complied by campaign group WiFi In Schools.

The papers listed are only those where exposures were 16V/m or below.  Someone using a Wi-Fi-enabled tablet computer can be exposed to electromagnetic fields up to 16V/m.  Papers are in alphabetical order.  A file of first pages, for printing, can be found here.

Image result for elf radiation

If you feel like sending a copy of this collection to the local schools in your area, you can search for them here and either print out this article to post or email the link.

Wi-Fi papers

1. Atasoy H.I. et al., 2013. Immunohistopathologic demonstration of deleterious effects on growing rat testes of radiofrequency waves emitted from conventional Wi-Fi devices. Journal of Pediatric Urology 9(2): 223-229. pubmed/22465825

2. Avendaño C. et al., 2012. Use of laptop computers connected to internet through Wi-Fi decreases human sperm motility and increases sperm DNA fragmentation. Fertility and Sterility 97(1): 39-45. pubmed/22112647

3. Avendaño C. et al., 2010. Laptop expositions affect motility and induce DNA fragmentation in human spermatozoa in vitro by a non-thermal effect: a preliminary report. American Society for Reproductive Medicine 66th Annual Meeting: O-249 wifiinschools.org.uk

4. Aynali G. et al., 2013. Modulation of wireless (2.45 GHz)-induced oxidative toxicity in laryngotracheal mucosa of rat by melatonin. Eur Arch Otorhinolaryngol 270(5): 1695-1700. pubmed/23479077

5. Gumral N. et al., 2009. Effects of selenium and L-carnitine on oxidative stress in blood of rat induced by 2.45-GHz radiation from wireless devices. Biol Trace Elem Res. 132(1-3): 153-163. pubmed/19396408

6. Havas M. et al., 2010. Provocation study using heart rate variability shows microwave radiation from 2.4GHz cordless phone affects autonomic nervous system. European Journal of Oncology Library Vol. 5: 273-300. icems.eu/papers part 2

7. Havas M. and Marrongelle J. 2013. Replication of heart rate variability provocation study with 2.45GHz cordless phone confirms original findings. Electromagn Biol Med 32(2): 253-266. pubmed/23675629

8. Maganioti A. E. et al., 2010. Wi-Fi electromagnetic fields exert gender related alterations on EEG. 6th International Workshop on Biological Effects of Electromagnetic fields. istanbul.edu.tr

9. Margaritis L.H. et al., 2013. Drosophila oogenesis as a bio-marker responding to EMF sources.
Electromagn Biol Med., Epub ahead of print. pubmed/23915130

10. Naziroğlu M. and Gumral 2009. Modulator effects of L-carnitine and selenium on wireless devices (2.45 GHz)-induced oxidative stress and electroencephalography records in brain of rat. Int J Radiat Biol. 85(8): 680-689. pubmed/19637079

11. Nazıroğlu M. et al., 2012. 2.45-Gz wireless devices induce oxidative stress and proliferation through cytosolic Ca2+ influx in human leukemia cancer cells. International Journal of Radiation Biology 88(6): 449–456. pubmed/22489926

12. Nazıroğlu M. et al., 2012b. Melatonin modulates wireless (2.45 GHz)-induced oxidative injury through TRPM2 and voltage gated Ca(2+) channels in brain and dorsal root ganglion in rat. Physiol Behav. 105(3): 683-92. pubmed/22019785

13. Oksay T. et al., 2012. Protective effects of melatonin against oxidative injury in rat testis induced by wireless (2.45 GHz) devices. Andrologia doi: 10.1111/and.12044, Epub ahead of print. pubmed/23145464

14. Papageorgiou C. C. et al., 2011. Effects of Wi-Fi signals on the p300 component of event-related potentials during an auditory hayling task. Journal of Integrative Neuroscience 10(2): 189-202. pubmed/21714138 (Wi-Fi alters brain activity in young adults: wifiinschools.org.uk)

15. Shahin S. et al., 2013. 2.45 GHz Microwave Irradiation-Induced Oxidative Stress Affects Implantation or Pregnancy in Mice, Mus musculus. Appl Biochem Biotechnol 169: 1727–1751. pubmed/23334843

16. Türker Y. et al., 2011. Selenium and L-carnitine reduce oxidative stress in the heart of rat induced by 2.45-GHz radiation from wireless devices. Biol Trace Elem Res. 143(3): 1640-1650. pubmed/21360060

And here are a few more studies of similar microwave frequencies at low exposures (6V/m or below)  (this is not comprehensive):

17. Balmori A. 2010. Mobile phone mast effects on common frog (Rana temporaria) tadpoles: the city turned into a laboratory. Electromagn. Biol. Med. 29(1-2):31-35. pubmed/20560769

18. Erdinc O. O. et al., 2003. Electromagnetic waves of 900MHz in acute pentylenetetrazole model in ontogenesis in mice. Neurol. Sci. 24:111-116 pubmed/14600821

19. Fesenko E. E. et al., 1999. Stimulation of murine natural killer cells by weak electromagnetic waves in the centimeter range. Biofizika 44:737–741 pubmed/10544828

20. Fesenko E. E. et al., 1999. Microwaves and cellular immunity. I. Effect of whole body microwave irradiation on tumor necrosis factor production in mouse cells, Bioelectrochem. Bioenerg. 49:29–35 pubmed/10619445

21. Havas M. et al., 2010. Provocation study using heart rate variability shows microwave radiation from 2.4GHz cordless phone affects autonomic nervous system. European Journal of OncologyLibrary Vol. 5: 273-300 icems.eu part 2.

22. Kesari K. K. and Behari J., 2009. Microwave exposure affecting reproductive system in male rats. Appl. Biochem. Biotechnol. 162(2):416-428 pubmed/19768389

23. Kesari K. K. and Behari J., 2009. Fifty-gigahertz microwave exposure effect of radiations on rat brain. Appl. Biochem. Biotechnol. 158:126-139 pubmed/19089649

24. Khurana V. G. et al., 2010. Epidemiological Evidence for a Health Risk from Mobile Phone Base Stations. Int. J. Occup. Environ. Health 16:263–267 pubmed/20662418

25. Maier R. et al., 2004. Effects of pulsed electromagnetic fields on cognitive processes – a pilot study on pulsed field interference with cognitive regeneration. Acta Neurologica Scandinavica 110: 46-52 pubmed/15180806

26. Nittby H. et al., 2008. Cognitive impairment in rats after long-term exposure to GSM-900 mobile phone radiation. Bioelectromagnetics 29: 219-232 pubmed/18044737

27. Novoselova E. G. et al., 1998. Stimulation of production of tumor necrosis factor by murine macrophages when exposed in vivo and in vitro to weak electromagnetic waves in the centimeter range Bofizika 43:1132–1333.

28. Novoselova E. G. et al., 1999. Microwaves and cellular immunity. II. Immunostimulating effects of microwaves and naturally occurring antioxidant nutrients. Bioelectrochem. Bioenerg. 49:37–41 pubmed/10619446

29. Otitoloju A. A. et al., 2010. Preliminary study on the induction of sperm head abnormalities in mice, Mus musculus, exposed to radiofrequency radiations from Global System for Mobile Communication Base Stations. Bull. Environ. Contam. Toxicol. 84(1):51-4. pubmed/19816647

30. Panagopoulos D. J.et al., 2010. Bioeffects of mobile telephony radiation in relation to its intensity or distance from the antenna. Int. J. Radiat. Biol. Vol 86(5):345-357. pubmed/20397839

31. Persson B. R. R. et al., 1997. Blood-brain barrier permeability in rats exposed to electromagnetic fields used in wireless communication. Wireless Networks 3: 455-461.

32. Pyrpasopoulou A. et al., 2004. Bone morphogenic protein expression in newborn kidneys after prenatal exposure to radiofrequency radiation. Bioelectromagnetics 25:216-27 pubmed/15042631

33. Salford L. G. et al., 2010. Effects of microwave radiation upon the mammalian blood-brain barrier. European Journal of Oncology Library Vol. 5:333-355 icems.eu part 2.

34. Salford L. G., et al., 2003. Nerve cell damage in mammalian brain after exposure to microwaves from GSM mobile phones. Environ. Health Perspect. 111:881-883. pubmed/12782486

With thanks to WifiInSchools.

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